Dual Operator Glove Box Workstation with Balance Enclosure
Occasionally, containment devices must be made a bit more complex in order to simplify the process taking place inside. Here, a powder ingredient can be manipulated in a 2- stage process involving a Mettler analytical balance and a Senco FC202 glass-jacketed reactor using a dual operator glove box workstation with balance enclosure. This containment device …
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Fitzmill L1A & Quadro Comil Glovebox
Glovebox Workstation Glovebox and Comil Glovebox and Fitzmill Process:Flow Sciences was approached to design a glovebox that would enclose milling processes done by either a Fitzmill L1A or a Quadro Comil. Containment Design:A panel interface on the right side of the glovebox allowed for the connection of either piece of equipment that would sit on …
HPAPI Processing and Drying Suite
HPAPI Processing and Drying Suite Purpose: A two-part enclosure consisting of a Single Pass Air Flow Glove Box Enclosure and a Nitrogen Purge Enclosure was designed to provide protection to the operator and product. The left side uses HEPA-filtered supply air as well as HEPA exhaust to create a clean interior environment, while the right …
Issues with Weighing in a Ventilated Enclosure
Dr. Robert Haugen, Flow Sciences Inc. Abstract: The use of weighing equipment in all chemical and pharmaceutical endeavors is critical. In chemical research, the accurate measurement of a reaction product may directly lead to its chemical formula. In pharmacy, dry weight of a drug becomes central to administering proper dosage. Examples of the criticality of …
Memmert VO 200 Vacuum Oven Enclosure
Memmert VO 200 Vacuum Oven Enclosure Finding a solution to provide personnel protection when working with Highly Potent Active Pharmaceutical Ingredients (HPAPI) is very tricky. In a business sector where regulations and policies are prevalent, exposure control options are limiting; both physically and financially. Laboratory operations require unwavering precision and physical/financial …
Fume Hood Sash Glass: What Do Standards and Specifications Require?
Robert Haugen, Ph.D., Flow Sciences Abstract: The most obvious barrier between a lab worker and a potential experimental accident is the fume hood sash. Ideally, we want such a sash to protect the researcher from eruptions, spatters, and other dangers present in typical reactive chemistry. Like many other issues involving materials of construction, fume hood …
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Containment Using a Non-Reactive Atmosphere
Dr. Bob HaugenDirector of Product and Technology Development Gary DeanMechanical Designer What happens when the air itself becomes a threat to whatever process is being undertaken? Abstract: There are frequent cases where the atmosphere we live in every day can become a laboratory hazard. The earth’s atmosphere contains Nitrogen (78%), Oxygen (21%), Argon (1%), and …
Chemical Fume Hoods : Four Truths about Price
Dr. Robert K. HaugenFlow Sciences, Inc. Abstract: Flow Sciences manufactures containment equipment for the pharmaceutical, chemistry, and education communities. Like many manufacturers serving these customers, we try to build products that work. Particularly with safety equipment, we believe providing protection from fumes and toxic powders is a mission worthy and beneficial to mankind. We do …
Designing Engineering Controls for High Potency Containment
Engineering Controls are Necessary to Extract and Remove Toxins to Prevent Inhalation, Dermal, and Other Exposures as well as Cross Contamination of Samples. CONTAINMENT CHALLENGE: RISK ASSESSMENT Personnel and/or product protection is imperative for the safety of operators and the liability of companies that manufacture and manipulate toxic materials. Arriving at a solution requires careful consideration …
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Genevac EZ2 Elite Evaporator and Powder Handling Suite
Genevac EZ2 Elite Evaporator and Powder Handling Suite Flow Sciences, Inc. was tasked with designing a modular containment unit that would house a Genevac EZ2 Elite Evaporator and allow for transfer of materials post-manipulation into a separate, connected balance enclosure for weighing. The Genevac equipment required a level, sturdy work surface and a 2” …
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Evaluating a Chemical Fume Hood for Containment of Solids, Liquids, and Vapors Using ASHRAE 110, HAM, and ISPE Methods
Allan Goodman, Ph.D., Flow SciencesRobert Haugen, Ph.D., Flow Sciences Abstract: Flow Sciences has more than three decades of experience in designing, manufacturing and testing powder containment devices, predominantly for the pharmaceutical industry. These enclosures have evolved from small balance containment devices connected to remote blowers, to a variety of custom and standard products. This increased …
Fume Hood Fire Issues above the Duct Collar
Dr. Bob HaugenDirector of Product and Technology DevelopmentFlow Sciences, Inc. Abstract: We have already looked at accidents inside fume hoods and posed several questions that might rush through one’s mind directly after a fume hood fire erupts 1. From this earlier paper referenced above and an additional literature search we will examine the following issues in this …
The Galaxy of Containment Devices
Robert K. Haugen, Ph.D. Director of Product and Technology Development Flow Sciences, Inc. ABSTRACT: The galaxy of laboratory containment devices is incredibly diverse. While many segments of this industry have developed their own categories of classification 1, no overarching system of categories has ever been developed for the entire lab containment equipment industry. We …
FSI and IsoTech Enter Strategic Alliance for Non-Sterile and Sterile Containment
Flow Sciences Inc., Leland, NC and Isotech Design, Montreal (Quebec) Canada announce the formation of a strategic business alliance. This will promote the sales of one another’s products in North America and internationally to provide non-sterile and sterile solutions to pharma, biopharma, nanotechnology, pharmacy, and other industries. Flow Sciences, Inc., a recognized thought leader in the …
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Summary, Containment Testing of Saf T Flow Chemical Fume Hoods
Over a period of time ranging from 11/6/2013 onward, the range of standard Saf T Flow Fume Hoods shown below were tested by Flow Sciences using the ASHRAE 110-1995 methodology. Details of the individual tests are available separately from Flow Sciences; total results are summarized below: ASHRAE 110-2016 Saf T Flow Test Data Summarized by …
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Less Downtime, More Productivity: FSI Systems Cost of Ownership
Flow Sciences, a leading provider of containment systems for laboratory, pilot plant, and manufacturing facilities, delivers low cost of ownership and high return on investment. By utilizing sophisticated engineering and design into the construction of the systems, they are able to achieve less lab downtime, more consistent results, no cross-contamination, and less energy consumption. Q: …
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Stainless Steel Malvern 3000 Enclosure
Application: Small Volume Liquid Dispersion Analysis with Getinge La Calhene Alpha-Beta Ports This stainless steel enclosure was designed for small volume liquid dispersion/particle size distribution analysis methods involving Highly Potent Active Pharmaceutical Ingredients (HPAPIs). Particularly, it was designed for operations conducted in facilities operating under the stipulations of current Good Manufacturing Practices (cGMPs). The working …
Thinking Outside the Box: 10 Considerations For Balance Stability
ABSTRACT: Stability of your weighing balance is paramount when it comes to collecting reliable data for project. As the old adage goes, “Anything that can go wrong will go wrong.”. Depending on the problem, taking obvious action for a seemingly obvious solution may not result in success. The purpose of this paper is to inspire …
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How Does the FSI Fume Hood Stack up on The Top Ten Lab Worker Needs?
Abstract: Lab Manager magazine1 recently published a feature entitled Survey Says. In this article was a section called “What You Need to Know Before Buying a Fume Hood.” Ten factors were named in over half the lab managers surveyed. We will review and analyze these factors and discuss how Flow Sciences addresses them. Whatever we’re doing, …
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