Collaborative Performance Validation – Safebridge Consultants, Inc. and Flow Sciences, Inc.

Employees of a pharmaceutical manufacturing facility were producing synthesized estrogen, a female reproductive hormone. Some male workers exhibited symptoms of exposure to female hormones. In response, four Syntax employees collaborated with four other pharmaceutical companies to develop standards to prevent and attenuate exposure to pharmaceutical substances with unknown health effects. The efforts of all parties involved became the predecessor to the control banding policies which are practiced by many pharmaceutical companies today. The business collaborative was also a prelude to the founding of Safebridge Consultants, Inc.  Flow Sciences, Inc. utilizes Safebridge’s Industrial Hygiene and Toxicological expertise for numerous purposes. A demonstrative example is the development of a Containment Performance Target (CPT) for substances with unknown health effects.

Containment Performance Target (CPT) – customer defined level of acceptance exposure to personnel from potentially harmful materials handled in the process

Flow Sciences uses the CPT as a reference metric when validating the performance of enclosure through in-house testing. The concentration results of air samples taken in locations surrounding the enclosure and in the breathing zone of the simulation operators are compared to the CPT, which leads to a determination on whether the tested enclosure will contain contaminants to a concentration below the CPT. For more information regarding Flow Sciences’ internal performance validation testing, please visit the Performance webpage.

During selected containment projects, Flow Sciences, Inc. contracts Safebridge personnel to perform a Site Acceptance Test (SAT). The SAT is similar to that of Flow Sciences’ in-house performance validation; however the SAT is conducted on-site under simulated conditions similar to those present during the real-world use of the enclosure. Controlled, prescribed tasks are performed by simulation operators in accordance with the customer’s standard operating procedures (SOPs). If worst-case scenario (or catastrophic condition) testing is advantageous to the customer, breathing zone and area air samples are collected and the laboratory results compared to the CPT and/or internal metrics at the customer’s discretion or prerogative.

Another Flow Sciences, Inc. and Safebridge Consultants, Inc. Collaboration.

Share on linkedin
Share on facebook
Share on twitter
Scroll to Top

Flow Sciences Newsletter Sign Up

Sign up now to receive news, product updates, white papers, and more!


This field is for validation purposes and should be left unchanged.


  • Is this similar to a TaskMatch enclosure or Standard enclosure? Enter the Enclosure ID or TaskMatch link here.
  • What is being done inside of the enclosure? What type of material (powder, liquid, gas, nuisance odor) is being worked with? How does the material enter and exit the enclosure system? etc...
  • What type of filtration is required? Single HEPA, Dual HEPA, Carbon, House Exhaust, etc... What is the required OEL (Occupational Exposure Limit) for the process, or any other details about containment goals? What is the quantity of powder or liquid, task duration, composition of powder, etc...?
  • What equipment is being worked with? What is the equipment model, size, scope, function, and any other information that will affect the design of the enclosure, including movement, heat output, etc...? *State the specific equipment make and model if available*
  • Are there any details on the facility that could affect the design of the enclosure including ceiling height, install door width, installation path, docks, available CFM, etc...? Any special shipping instructions such as required disassembly, flat packing, etc...?
  • When are you looking to have this unit installed and ready for use? Are there any other details about the project that should be considered? Is this part of a construction or renovation project?
  • Do you need a table or cabinet and if so, do you require any special features such as shelf, extension, equipment support, etc.? Would you prefer 304 or 316 SS or a powder coated mild steel? What working height would you like? Do you need it to be stationary or movable? Lift (adjustable height) or fixed height?
  • Drop files here or
    Max. file size: 256 MB.
    • Are there any additional notes or information that should be considered? Are there any special design requirements?
    • Hidden
    • This field is for validation purposes and should be left unchanged.