Flow Sciences’ team of containment experts are challenged with providing solutions for complex applications.  These projects are mostly equipment specific, and focus on the localized containment of the procedure while providing personnel and/or product protection.

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CONTAINMENT PROJECTS


PERFORMANCE TESTING

Performance is paramount in the safety industry. Through consistent design quality and expert manufacturing, Flow Sciences’ units perform.  With surrogate powder testing both in our facility as factory acceptance testing (FAT) and at the customer facility as site acceptance testing (SAT), we consistently exceed our customers’ containment targets and goal expectations.

FLOW SCIENCES CONTAINS.  FLOW SCIENCES PERFORMS.

HIGH POTENCY GLOVEBOX WORKSTATION SYSTEM

Containment Target : 50 ng/m³
Surrogate Powder Testing Result :  0.4 ng/m³

Equipment : Balances
Operation : Weighing / Transferring
Test : Naproxen Sodium – 3 x 500g

API WEIGHING & SOLID DOSING SUITE

Containment Target : 10 ng/m³
Surrogate Powder Testing Result :  2.26 ng/m³

Equipment : Balance, Vials
Operation : Weighing, Dissolution, Dispensing
Test : Naproxen Sodium – 3 x 20mg

BULK POWDER BAG WEIGHING ENCLOSURE

Containment Target : 1,000 ng/m³
Surrogate Powder Testing Result :  4 ng/m³

Equipment : Balance, Bulk Powder Bag
Operation : Bulk Powder Weighing
Test : Lactose – 3 x 15 kg

STAINLESS STEEL GLOVEBOX FOR CYTOTOXIC DRUG DEVELOPMENT

Containment Target : 5 ng/m³
 Surrogate Powder Testing Result :  0.12 ng/m³

Equipment : Balance
Operation : Weighing, Dissolution
Test : Naproxen Sodium – 3 x 10g

API PROCESS DEVELOPMENT SYSTEM

Containment Target : 1,000 ng/m³
Surrogate Powder Testing Result :  0.51 ng/m³

Equipment : Balance, Filter, Vacuum Oven
Operation : Weighing, Filtering
Test : Lactose – 3 x 500g

BUCHI B-290 MINI-SPRAY DRYER ENCLOSURE

Containment Target : 1,000 ng/m³
 Surrogate Powder Testing Result :  0.32 ng/m³

Equipment : Spray Dryer
Operation : Spray Drying
Test : Naproxen Sodium – 3 x 50g

SYMPATEC INHALER ENCLOSURE

Containment Target : 50 ng/m³
Surrogate Powder Testing Result :  0.28 ng/m³

Equipment : Funnel, Weigh Boat
Operation : Sympatec Simulation, Cleaning
Test : Naproxen Sodium – 3 x 3.0g

GENEVAC EZ2 ELITE POWDER HANDLING SUITE

Containment Target : 100 ng/m³
Surrogate Powder Testing Result :  35 ng/m³

Equipment : Balance, Genevac
Operation : Weighing / Dissolution
Test : Lactose – 60g

CLASS I BSC – DUAL HEPA

Containment Target : 50 ng/m³
 Surrogate Powder Testing Result :  0.1 ng/m³

Equipment : Funnel, Balance
Operation : Weighing, Transferring

KARL FISCHER GT-TIX TITRATOR SYSTEM AND METTLER BALANCE ENCLOSURE

Containment Target : 1,000 ng/m³
Surrogate Powder Testing Result :  Non-Detect

Equipment : Corning Tubes
Operation : Karl Fischer Titrator Simulation
Test : Lactose – 31 x 0.1g

STAINLESS STEEL VENTED ENCLOSURE

Containment Target : 100 ng/m³
Surrogate Powder Testing Result :  0.06 ng/m³

Equipment : Balance
Operation : Sympatec Simulation, Cleaning
Test : Naproxen Sodium – 3 x 100g

LINDBERG/BLUE M VACUUM OVEN

Containment Target : 500 ng/m³
 Surrogate Powder Testing Result :  4 ng/m³

Equipment : Balance, Oven
Operation : Simulated Drying, Bulk Transfer
Test : Naproxen Sodium – 3 x 500g

TITRATION ENCLOSURE

Containment Target : 100 ng/m³
Surrogate Powder Testing Result :  4 ng/m³

Equipment : Corning Tubes
Operation : Karl-Fischer Simulation
Test : Naproxen Sodium – 31 x 0.1g

SP SCIENTIFIC LYOSTAR II FREEZE DRYING GLOVEBOX

Containment Target : 50 ng/m³
Surrogate Powder Testing Result :  12 ng/m³

Equipment : Vials
Operation : Equipment Loading

N15 WEIGHT SORTER ENCLOSURE

Containment Target : 50 ng/m³
Surrogate Powder Testing Result :  Non-Detect

Equipment : Trays
Operation : Pill Sorting
Test : Naproxen Sodium – 3 x 400 pills (220g)

PARTICLE ANALYSIS SUITE

Containment Target : 100 ng/m³
Surrogate Powder Testing Result :  8 ng/m³

Equipment : Nilfisk
Operation : Sympatec Simulation, Cleaning
Test : Naproxen Sodium – 30 x 0.1g

BUCHI SPRAY DRYER SYSTEM

Containment Target : 100 ng/m³
 Surrogate Powder Testing Result :  6 ng/m³

Equipment : Glassware
Operation : Spray Dryer Cleaning
Test : Naproxen Sodium – 3 x 5g

HIGH POTENCY API PREP SYSTEM

Containment Target : 200 ng/m³
Surrogate Powder Testing Result :  9 ng/m³

Equipment : Balances, Mortar & Pestle
Operation : Weighing, Grinding
Test : Lactose – 3 x 500g

POLYPROPYLENE BULK POWDER ENCLOSURE

Containment Target : 40 μg/m³
Surrogate Powder Testing Result :  3.82 μg/m³

Equipment : Balance, Scoops
Operation : Weighing, Bulk Powder Dispensing
Test : Lactose – 3 x 25kg

STAINLESS STEEL BULK POWDER ENCLOSURE

Containment Target: 100 ng/m³
Surrogate Powder Testing Result :  3 ng/m³

Equipment : Balance
Operation : Weighing
Test : Naproxen Sodium – 3 x 100g

INSTRON 3367 TENSILE TESTING ENCLOSURE

Containment Target : 1,000 ng/m³
 Surrogate Powder Testing Result :  0.12 ng/m³

Equipment : Die and Press
Operation : Tablet Making
Test : Naproxen Sodium – 20g

SIEVING SUITE

Containment Target : 50 ng/m³
Surrogate Powder Testing Result :  1 ng/m³

Equipment : Sieve Shaker
Operation : Sieve Shaking
Test : Naproxen Sodium – 3 x 500g


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