Continuous Process Isolator for Product & Personnel Protection

The Analytical Process Isolator™ or A.P.I. is a continuous process isolator to vented enclosure system that allows for ISO 5 clean processing and intake or outtake through a negative pressure vented cabinet.


  •  Proprietary Lateral Flow Bio Containment™ LFBC™ ISO 5 Lateral Flow Interior Glove Box Isolator for Personnel & Product Protection
  •  Vented Enclosure with Negative Pressure Connected through a proprietary space-saving Door Design for Secondary Cleaning or Decontamination
  •  Lateral Flow or Smooth Horizontal Airflow Across the Isolator Prevents Disturbance on the Work Surface or When Sampling
  •  4″ Pleated HEPA Inlet filter, as well as Dual HEPA BIBO (Bag-In/Bag-Out) Exhaust Stacks on the Isolator Side and Vented Enclosure Side Allow for Recirculation of Clean Air into the Lab
  •  Without Customization, the Analytical Process Isolator has an 8-10 WEEK Lead Time
  •  Surrogate Powder Test Results show Proven Containment Below 10 ng/m3, Even with Catastrophic Spill


Sample Application:  Highly Potent API Weighing & Sampling
Weighing and solution prep with 10g of OEB 5 powder, then transfer into vented enclosure for secondary cleaning. Containment Performance Target: to work with the OEB 4 and OEB 5 APIs, the customer required 10ng/m3 (ten nanograms per meter cubed) at the breathing zone of the operator, as well as ISO 5 or better interior cleanliness.


Sample Application:  High Throughput Virus Screening
Screening or PCR of 96 well plate of virus samples in a dual protection (product & personnel protection) isolator.  The ISO 5 interior cleanliness keeps the integrity of the samples, while the less than 10 ng/m3 containment ensures safety for the operator. Containment Performance Target: Product and Personnel Protection while sampling highly potent or toxic materials, including infectious virus screening.

Contact Flow Sciences for More Information

  • What is being done inside of the enclosure? What type of material (powder, liquid, gas, nuisance odor) is being worked with? How does the material enter and exit the enclosure system? etc...
  • What type of filtration is required? Single HEPA, Dual HEPA, Carbon, House Exhaust, etc... What is the required OEL (Occupational Exposure Limit) for the process, or any other details about containment goals? What is the quantity of powder or liquid, task duration, composition of powder, etc...?
  • What equipment is being worked with? What is the equipment model, size, scope, function, and any other information that will affect the design of the enclosure, including movement, heat output, etc...? *State the specific equipment make and model if available*
  • Are there any additional notes or information that should be considered? Are there any special design requirements?